Found 64 hits with Last Name = 'armando' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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| n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| Article PubMed
| n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
Group XIIB secretory phospholipase A2-like protein
(Homo sapiens) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | KEGG
UniProtKB/SwissProt
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| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant sPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
Group XIIB secretory phospholipase A2-like protein
(Homo sapiens) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant sPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| Article PubMed
| n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
Group XIIB secretory phospholipase A2-like protein
(Homo sapiens) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant sPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
Group XIIB secretory phospholipase A2-like protein
(Homo sapiens) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant sPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid PDB UniChem
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| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
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| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50055366
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |
85/88 kDa calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50529953
(CHEMBL4438490)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26+/t37-,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71 |
More data for this Ligand-Target Pair | |