| Reaction Details |
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 | Report a problem with these data |
| Target | Group XIIB secretory phospholipase A2-like protein |
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| Ligand | BDBM50055366 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1911015 (CHEMBL4413461) |
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| IC50 | 131±n/a nM |
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| Citation |  Mouchlis, VD; Armando, A; Dennis, EA Substrate-Specific Inhibition Constants for Phospholipase A J Med Chem62:1999-2007 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Group XIIB secretory phospholipase A2-like protein |
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| Name: | Group XIIB secretory phospholipase A2-like protein |
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| Synonyms: | GXIIB | GXIII sPLA2-like | Group XIIB secretory phospholipase A2-like protein | Group XIII secretory phospholipase A2-like protein | PG12B_HUMAN | PLA2G12B | PLA2G13 | PLA2G13 | sPLA2-GXIIB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21657.53 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119722 |
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| Residue: | 195 |
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| Sequence: | MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGK
NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD
TCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNS
QRAACICAEEEKEEL
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| BDBM50055366 |
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| n/a |
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| Name | BDBM50055366 |
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| Synonyms: | (3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-acetic acid | (3-Aminooxalyl-1-benzyl-2-ethyl-2,3-dihydro-1H-indol-4-yloxy)-acetic acid | 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid | CHEMBL148674 | Varespladib sodium |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20N2O5 |
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| Mol. Mass. | 380.3939 |
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| SMILES | CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 |
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| Structure | 
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