| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase A1 |
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| Ligand | BDBM50530228 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1911517 (CHEMBL4413963) |
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| Ki | 0.530000±n/a nM |
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| Citation |  Covaleda, G; Gallego, P; Vendrell, J; Georgiadis, D; Lorenzo, J; Dive, V; Aviles, FX; Reverter, D; Devel, L Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. J Med Chem62:1917-1931 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase A1 |
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| Name: | Carboxypeptidase A1 |
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| Synonyms: | CBPA1_HUMAN | CPA | CPA1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47132.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1496378 |
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| Residue: | 419 |
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| Sequence: | MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG
SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA
TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS
REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR
SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK
AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA
SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
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| BDBM50530228 |
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| n/a |
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| Name | BDBM50530228 |
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| Synonyms: | CHEMBL4483485 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31N2O7P |
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| Mol. Mass. | 490.4859 |
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| SMILES | C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)P(O)(=O)C[C@@H](CCc1ccccc1)C(O)=O |r| |
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| Structure | 
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