| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50530586 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1913506 (CHEMBL4416089) |
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| Ki | 14±n/a nM |
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| Citation |  Mallo-Abreu, A; Majellaro, M; Jespers, W; Azuaje, J; Caamaño, O; García-Mera, X; Brea, JM; Loza, MI; Gutiérrez-de-Terán, H; Sotelo, E Trifluorinated Pyrimidine-Based A J Med Chem62:9315-9330 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50530586 |
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| n/a |
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| Name | BDBM50530586 |
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| Synonyms: | CHEMBL4585472 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14F3N3O3 |
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| Mol. Mass. | 377.3173 |
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| SMILES | CCOC(=O)C1=C(Nc2nc3ccccc3n2[C@@H]1c1ccoc1)C(F)(F)F |r,t:5| |
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| Structure | 
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