| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50532845 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1924015 (CHEMBL4426971) |
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| IC50 | 14000±n/a nM |
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| Citation |  Stanton, RA; Lu, X; Detorio, M; Montero, C; Hammond, ET; Ehteshami, M; Domaoal, RA; Nettles, JH; Feraud, M; Schinazi, RF Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorg Med Chem Lett26:4101-5 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50532845 |
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| n/a |
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| Name | BDBM50532845 |
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| Synonyms: | CHEMBL4532532 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13N3O |
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| Mol. Mass. | 227.2618 |
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| SMILES | CC(C)(C)n1cc(C#N)c2cc(C=O)cnc12 |
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| Structure | 
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