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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase | ||
| Ligand | BDBM50532856 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1924015 (CHEMBL4426971) | ||
| IC50 | 26000±n/a nM | ||
| Citation |  Stanton, RA; Lu, X; Detorio, M; Montero, C; Hammond, ET; Ehteshami, M; Domaoal, RA; Nettles, JH; Feraud, M; Schinazi, RF Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorg Med Chem Lett26:4101-5 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase | |||
| Name: | Reverse transcriptase | ||
| Synonyms: | n/a | ||
| Type: | Protein | ||
| Mol. Mass.: | 29598.37 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | Q9WKE8 | ||
| Residue: | 254 | ||
| Sequence: |
| ||
| BDBM50532856 | |||
| n/a | |||
| Name | BDBM50532856 | ||
| Synonyms: | CHEMBL4577153 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H27N3O | ||
| Mol. Mass. | 433.5442 | ||
| SMILES | Cc1cccc(C)c1-c1c2C(=O)CC(C)(C)Cc2nc2n(Cc3ccccc3)cc(C#N)c12 |(70.54,-26.87,;70.19,-28.41,;70.66,-29.87,;69.63,-31.02,;68.12,-30.7,;67.65,-29.2,;66.15,-28.85,;68.68,-28.09,;67.91,-25.75,;66.41,-25.44,;65.39,-26.58,;65.61,-28.11,;63.88,-26.25,;63.39,-24.76,;62.06,-25.54,;62.46,-23.57,;64.44,-23.65,;65.93,-23.97,;66.96,-22.83,;68.47,-23.15,;69.7,-22.24,;69.7,-20.7,;68.37,-19.92,;68.37,-18.38,;67.03,-17.62,;65.7,-18.39,;65.71,-19.94,;67.04,-20.7,;70.96,-23.14,;70.48,-24.61,;71.38,-25.86,;72.28,-27.11,;68.94,-24.61,)| | ||
| Structure | 
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