| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2b |
|---|
| Ligand | BDBM50534201 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1927920 (CHEMBL4430992) |
|---|
| Ki | >300±n/a nM |
|---|
| Citation |  Brunschweiger, A; Koch, P; Schlenk, M; Rafehi, M; Radjainia, H; Küppers, P; Hinz, S; Pineda, F; Wiese, M; Hockemeyer, J; Heer, J; Denonne, F; Müller, CE 8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors. Bioorg Med Chem24:5462-5480 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2b |
|---|
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36341.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 332 |
|---|
| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
|
|
|
|---|
| BDBM50534201 |
|---|
| n/a |
|---|
| Name | BDBM50534201 |
|---|
| Synonyms: | CHEMBL4552824 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H19F4N5O2 |
|---|
| Mol. Mass. | 425.3801 |
|---|
| SMILES | Cn1c2nc3CN(CCc4cc(ccc4F)C(F)(F)F)CCn3c2c(=O)n(C)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
