| Reaction Details |
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 | Report a problem with these data |
| Target | Stress-70 protein, mitochondrial |
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| Ligand | BDBM50539105 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1977650 (CHEMBL4610785) |
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| Kd | 3300±n/a nM |
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| Citation |  Gnanasekaran, KK; Pouland, T; Bunce, RA; Darrell Berlin, K; Abuskhuna, S; Bhandari, D; Mashayekhi, M; Zhou, DH; Benbrook, DM Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cells. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Stress-70 protein, mitochondrial |
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| Name: | Stress-70 protein, mitochondrial |
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| Synonyms: | 75 kDa glucose-regulated protein | GRP-75 | GRP75 | GRP75_HUMAN | HSPA9 | HSPA9B | Heat shock 70 kDa protein 9 | MOT | Mortalin | PBP74 | Peptide-binding protein 74 | Stress-70 protein, mitochondrial | mt-HSP70 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73676.63 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118002 |
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| Residue: | 679 |
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| Sequence: | MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDL
GTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYAT
KRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAEN
YLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVI
AVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTK
DNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIR
RTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIG
AAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQT
QVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTG
REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK
DQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE
GSGSSGTGEQKEDQKEEKQ
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| BDBM50539105 |
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| n/a |
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| Name | BDBM50539105 |
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| Synonyms: | CHEMBL4636437 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20F3N3S |
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| Mol. Mass. | 379.442 |
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| SMILES | CC1(C)CCNc2ccc(NC(=S)Nc3ccc(cc3)C(F)(F)F)cc12 |
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| Structure | 
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