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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cytochrome P450 4B1 | ||
| Ligand | BDBM50541296 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1984143 (CHEMBL4617549) | ||
| IC50 | >20000±n/a nM | ||
| Citation |  Myers, MC; Bilder, DM; Cavallaro, CL; Chao, HJ; Su, S; Burford, NT; Nayeem, A; Wang, T; Yan, M; Langish, RA; Dabros, M; Li, YX; Rose, AV; Behnia, K; Onorato, JM; Gargalovic, PS; Wexler, RR; Lawrence, RM Discovery and SAR of aryl hydroxy pyrimidinones as potent small molecule agonists of the GPCR APJ. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cytochrome P450 4B1 | |||
| Name: | Cytochrome P450 4B1 | ||
| Synonyms: | 1.14.14.1 | CP4B1_HUMAN | CYP4B1 | CYPIVB1 | Cytochrome P450 4B1 | Cytochrome P450-HP | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 59005.59 | ||
| Organism: | Homo sapiens | ||
| Description: | ChEMBL_119703 | ||
| Residue: | 511 | ||
| Sequence: |
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| BDBM50541296 | |||
| n/a | |||
| Name | BDBM50541296 | ||
| Synonyms: | CHEMBL4636169 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H16N2O3S | ||
| Mol. Mass. | 292.353 | ||
| SMILES | CCCSc1nc(=O)cc(O)n1-c1ccccc1OC |(38.91,-20.71,;40.24,-21.48,;41.58,-20.71,;42.91,-21.47,;44.24,-20.7,;44.25,-19.16,;45.58,-18.39,;45.58,-16.85,;46.91,-19.16,;46.91,-20.69,;48.25,-21.46,;45.58,-21.46,;45.58,-23,;44.25,-23.77,;44.25,-25.31,;45.58,-26.08,;46.92,-25.31,;46.91,-23.76,;48.24,-22.99,;49.58,-23.75,)| | ||
| Structure | 
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