| Reaction Details |
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 | Report a problem with these data |
| Target | Protein cereblon |
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| Ligand | BDBM65454 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1985380 (CHEMBL4618786) |
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| Ki | 1490±n/a nM |
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| Citation |  Kargbo, RB Ligand Design for Cereblon Based Immunomodulatory Therapy. ACS Med Chem Lett11:1088-1089 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein cereblon |
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| Name: | Protein cereblon |
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| Synonyms: | CRBN | CRBN_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50537.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116917 |
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| Residue: | 442 |
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| Sequence: | MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYL
GADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTF
AVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQA
KVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSW
PRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLK
IGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETL
TVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRS
ALLPTIPDTEDEISPDKVILCL
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| BDBM65454 |
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| n/a |
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| Name | BDBM65454 |
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| Synonyms: | 191732-72-6 | CC-5013 | Lenalidomide | Revimid | Revlimid | US11530219, Compound Lenalidomide | US9694015, 6.1 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13N3O3 |
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| Mol. Mass. | 259.2606 |
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| SMILES | Nc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O |
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| Structure | 
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