| Reaction Details |
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 | Report a problem with these data |
| Target | Gonadotropin-releasing hormone receptor |
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| Ligand | BDBM50099023 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_71581 |
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| IC50 | 170±n/a nM |
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| Citation |  Lin, P; Marino, D; Lo, JL; Yang, YT; Cheng, K; Smith, RG; Fisher, MH; Wyvratt, MJ; Goulet, MT 2-(3,5-Dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor. Bioorg Med Chem Lett11:1073-6 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gonadotropin-releasing hormone receptor |
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| Name: | Gonadotropin-releasing hormone receptor |
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| Synonyms: | GNRHR | GNRHR_HUMAN | GRHR | GnRH receptor | GnRH-R | Gonadotropin releasing hormone 1 (GnRHR1) | Gonadotropin-releasing hormone receptor | Gonadotropin-releasing hormone receptor (GnRH) |
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| Type: | Enzyme |
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| Mol. Mass.: | 37749.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30968 |
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| Residue: | 328 |
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| Sequence: | MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL
QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM
IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR
VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL
SDPVNHFFFLFAFLNPCFDPLIYGYFSL
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| BDBM50099023 |
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| n/a |
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| Name | BDBM50099023 |
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| Synonyms: | CHEMBL11149 | N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]-ethylamino}-butyl)-phenyl]-methanesulfonamide | N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-2,3-dihydro-1H-indol-3-yl]-ethylamino}-butyl)-phenyl]-methanesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C29H35N3O2S |
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| Mol. Mass. | 489.672 |
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| SMILES | Cc1cc(C)cc(c1)-c1[nH]c2ccccc2c1CCNCCCCc1ccc(NS(C)(=O)=O)cc1 |
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| Structure | 
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