| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50099149 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_218126 |
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| EC50 | 75.0±n/a nM |
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| Citation |  Hu, B; Malamas, M; Ellingboe, J; Largis, E; Han, S; Mulvey, R; Tillett, J New oxadiazolidinedione derivatives as potent and selective human beta3 agonists. Bioorg Med Chem Lett11:981-4 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50099149 |
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| n/a |
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| Name | BDBM50099149 |
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| Synonyms: | 5-{4-[4-((S)-2-Hydroxy-3-phenoxy-propylamino)-piperidin-1-yl]-benzylidene}-2-piperidin-1-yl-thiazol-4-one | CHEMBL171963 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H36N4O3S |
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| Mol. Mass. | 520.686 |
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| SMILES | O[C@@H](CNC1CCN(CC1)c1ccc(\C=C2/SC(=NC2=O)N2CCCCC2)cc1)COc1ccccc1 |c:18| |
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| Structure | 
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