| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
|---|
| Ligand | BDBM50099153 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_218126 |
|---|
| EC50 | 230±n/a nM |
|---|
| Citation |  Hu, B; Malamas, M; Ellingboe, J; Largis, E; Han, S; Mulvey, R; Tillett, J New oxadiazolidinedione derivatives as potent and selective human beta3 agonists. Bioorg Med Chem Lett11:981-4 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-3 adrenergic receptor |
|---|
| Name: | Beta-3 adrenergic receptor |
|---|
| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 43534.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 408 |
|---|
| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
|
|
|
|---|
| BDBM50099153 |
|---|
| n/a |
|---|
| Name | BDBM50099153 |
|---|
| Synonyms: | CHEMBL451185 | N-[2-Hydroxy-5-(1-hydroxy-2-{1-[4-(2-imino-5-oxo-imidazolidin-4-ylmethyl)-phenyl]-piperidin-4-ylamino}-ethyl)-phenyl]-methanesulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H32N6O5S |
|---|
| Mol. Mass. | 516.613 |
|---|
| SMILES | CS(=O)(=O)Nc1cc(ccc1O)C(O)CNC1CCN(CC1)c1ccc(Cc2[nH]c(N)nc2O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
