Reaction Details |
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Target | Tubulin polymerization-promoting protein |
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Ligand | BDBM50099946 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_925239 (CHEMBL3073731) |
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EC50 | >100000±n/a nM |
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Citation | Young, DH; Tice, CM; Michelotti, EL; Roemmele, RC; Slawecki, RA; Rubio, FM; Rolling, JA Structure-activity relationships of phenylcyclohexene and biphenyl antitubulin compounds against plant and mammalian cells. Bioorg Med Chem Lett11:1393-6 (2001) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Tubulin polymerization-promoting protein |
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Name: | Tubulin polymerization-promoting protein |
Synonyms: | 25 kDa brain-specific protein | TPPP | TPPP_BOVIN |
Type: | PROTEIN |
Mol. Mass.: | 23484.86 |
Organism: | Bos taurus |
Description: | ChEMBL_106635 |
Residue: | 218 |
Sequence: | MADSRPKPANKTPPKSPGEPAKDKAAKRLSLEAEGAGEGAAAAGAELSALEEAFRKFAVH
GDARASGREMHGKNWSKLCRDCQVIDGRSVTVTDVDIVFSKIKGKSCRTITFEQFKEALE
ELAKKRFKDKSAEEAVREVHKLIEGKAPIISGVTKAISSPTVSRLTDTSKFTGSHKERFD
PSGRGKGRAGRVDLVDESGYVPGYKHAGTYDQKVQGGK
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BDBM50099946 |
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n/a |
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Name | BDBM50099946 |
Synonyms: | 1,2,3-Trimethoxy-4-(6-nitro-cyclohex-3-enyl)-benzene | CHEMBL283411 |
Type | Small organic molecule |
Emp. Form. | C15H19NO5 |
Mol. Mass. | 293.3151 |
SMILES | COc1ccc(C2CC=CC[C@H]2[N+]([O-])=O)c(OC)c1OC |c:8| |
Structure |
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