| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Apelin receptor |
|---|
| Ligand | BDBM50544719 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1993688 (CHEMBL4627583) |
|---|
| EC50 | 3700±n/a nM |
|---|
| Citation |  Narayanan, S; Vasukuttan, V; Rajagopal, S; Maitra, R; Runyon, SP Identification of potent pyrazole based APELIN receptor (APJ) agonists. Bioorg Med Chem28:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Apelin receptor |
|---|
| Name: | Apelin receptor |
|---|
| Synonyms: | AGTRL1 | APJ | APJ_HUMAN | APLNR | Angiotensin receptor-like 1 | Apelin receptor | Apelin receptor (APJ) | G-protein coupled receptor APJ | G-protein coupled receptor HG11 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42664.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35414 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK
RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL
TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ
CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL
RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV
NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK
GGEQMHEKSIPYSQETLVVD
|
|
|
|---|
| BDBM50544719 |
|---|
| n/a |
|---|
| Name | BDBM50544719 |
|---|
| Synonyms: | CHEMBL4645831 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21NO4S |
|---|
| Mol. Mass. | 359.439 |
|---|
| SMILES | CC1=CC(=O)C(=C\C1=N/OS(=O)(=O)c1ccccc1)C1CCCCC1 |c:5,t:1| |
|---|
| Structure | 
|
|---|
Search and Browse
