| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin G/H synthase 2 |
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| Ligand | BDBM50105296 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157858 |
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| IC50 | 10500±n/a nM |
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| Citation |  Feixas, J; Jiménez, JM; Godessart, N; Puig, C; Soca, L; Crespo, MI Naphthalene derivatives: A new series of selective cyclooxygenase-2 inhibitors. Bioorg Med Chem Lett11:2687-90 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin G/H synthase 2 |
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| Name: | Prostaglandin G/H synthase 2 |
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| Synonyms: | Cox-2 | Cox2 | Cyclooxygenase | PGH2_RAT | Ptgs2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 69173.51 |
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| Organism: | RAT |
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| Description: | COX-2 0 RAT::P35355 |
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| Residue: | 604 |
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| Sequence: | MLFRAVLLCAALALSHAANPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFL
TRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNVHY
GYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGT
NMMFAFFAQHFTHQFFKTDQKRGPGFTRGLGHGVDLNHVYGETLDRQHKLRLFQDGKLKY
QVIGGEVYPPTVKDTQVDMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCD
ILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ
NRIASEFNTLYHWHPLLPDTFNIEDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRV
AGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKAL
YHDIDAMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEV
GFRIINTASIQSLICNNVKGCPFASFNVQDPQPTKTATINASASHSRLDDINPTVLIKRR
STEL
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| BDBM50105296 |
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| n/a |
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| Name | BDBM50105296 |
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| Synonyms: | CHEMBL91595 | [4-(4-Chloro-benzyl)-7-methoxy-naphthalen-2-yl]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17ClO3 |
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| Mol. Mass. | 340.8 |
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| SMILES | COc1ccc2c(Cc3ccc(Cl)cc3)cc(CC(O)=O)cc2c1 |
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| Structure | 
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