Reaction Details | |||
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Target | Melanocortin receptor 3 | ||
Ligand | BDBM50033134 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_220872 (CHEMBL824628) | ||
Ki | 140±n/a nM | ||
Citation | Bednarek, MA; MacNeil, T; Kalyani, RN; Tang, R; Van der Ploeg, LH; Weinberg, DH Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro. J Med Chem44:3665-72 (2001) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Melanocortin receptor 3 | |||
Name: | Melanocortin receptor 3 | ||
Synonyms: | MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4) | ||
Type: | Enzyme | ||
Mol. Mass.: | 36044.86 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41968 | ||
Residue: | 323 | ||
Sequence: |
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BDBM50033134 | |||
n/a | |||
Name | BDBM50033134 | ||
Synonyms: | (3R,6S,9R,12S,15S,23R)-15-((S)-2-Acetylamino-hexanoylamino)-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-naphthalen-2-ylmethyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide | 15-(2-Acetylamino-hexanoylamino)-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-naphthalen-2-ylmethyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid | CHEMBL266417 | ||
Type | Small organic molecule | ||
Emp. Form. | C54H71N15O9 | ||
Mol. Mass. | 1074.2366 | ||
SMILES | CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O | ||
Structure |