| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50106067 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_213047 |
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| IC50 | >10000±n/a nM |
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| Citation |  Su, T; Wu, Y; Doughan, B; Jia, ZJ; Woolfrey, J; Huang, B; Wong, P; Park, G; Sinha, U; Scarborough, RM; Zhu, BY Design, synthesis, and SAR of amino acid derivatives as factor Xa inhibitors. Bioorg Med Chem Lett11:2947-50 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50106067 |
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| n/a |
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| Name | BDBM50106067 |
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| Synonyms: | (S)-4-(3-Carbamimidoyl-benzoylamino)-4-(2'-sulfamoyl-biphenyl-4-ylcarbamoyl)-butyric acid | CHEMBL98306 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25N5O6S |
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| Mol. Mass. | 523.561 |
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| SMILES | NC(=N)c1cccc(c1)C(=O)N[C@@H](CCC(O)=O)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O |
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| Structure | 
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