| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50548794 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2023306 (CHEMBL4677119) |
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| Ki | 48978±n/a nM |
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| Citation |  Li, M; Huang, C; Wu, X; Ding, F; Hu, Z; Zhu, Y; Zhao, L; Hou, L; Chen, H; Wang, H; Xu, J; Tang, D The optimization of a novel selective antagonist for human M Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50548794 |
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| n/a |
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| Name | BDBM50548794 |
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| Synonyms: | CHEMBL4758742 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N3O |
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| Mol. Mass. | 335.4427 |
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| SMILES | CCn1c2ccccc2c2ccc(NCC(=O)N3CCCCC3)cc12 |
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| Structure | 
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