| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50549962 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2026016 (CHEMBL4679829) |
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| Ki | 1000±n/a nM |
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| Citation |  Kargbo, RB Sigma-1 and Sigma-2 Receptor Modulators as Potential Therapeutics for Alzheimer's Disease. ACS Med Chem Lett12:178-179 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20857.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q5BJF2 |
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| Residue: | 176 |
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| Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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| BDBM50549962 |
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| n/a |
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| Name | BDBM50549962 |
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| Synonyms: | CHEMBL4764493 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H32N4O |
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| Mol. Mass. | 440.5799 |
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| SMILES | O=C(N1CCCCC1)c1nn(c2CCC(Cc12)N1CCc2ccccc2C1)-c1ccccc1 |
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| Structure | 
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