| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin G/H synthase 1 |
|---|
| Ligand | BDBM50109681 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_159403 |
|---|
| IC50 | 140±n/a nM |
|---|
| Citation |  Kalgutkar, AS; Rowlinson, SW; Crews, BC; Marnett, LJ Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors. Bioorg Med Chem Lett12:521-4 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin G/H synthase 1 |
|---|
| Name: | Prostaglandin G/H synthase 1 |
|---|
| Synonyms: | COX1 | Cyclooxygenase-1 | Cyclooxygenase-1 (COX-1) | PGH1_SHEEP | PTGS1 | Prostaglandin G/H synthase (cyclooxygenase) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68868.60 |
|---|
| Organism: | Ovis aries (Sheep) |
|---|
| Description: | n/a |
|---|
| Residue: | 600 |
|---|
| Sequence: | MSRQSISLRFPLLLLLLSPSPVFSADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCT
RTGYSGPNCTIPEIWTWLRTTLRPSPSFIHFLLTHGRWLWDFVNATFIRDTLMRLVLTVR
SNLIPSPPTYNIAHDYISWESFSNVSYYTRILPSVPRDCPTPMDTKGKKQLPDAEFLSRR
FLLRRKFIPDPQSTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLER
QYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLML
YATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLK
FDPELLFGAQFQYRNRIAMEFNQLYHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVE
ALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQE
LTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPIC
SPEYWKASTFGGEVGFNLVKTATLKKLVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL
|
|
|
|---|
| BDBM50109681 |
|---|
| n/a |
|---|
| Name | BDBM50109681 |
|---|
| Synonyms: | 2-(2,6-Dichloro-3-methyl-phenylamino)-N-(2-methoxy-ethyl)-benzamide | CHEMBL149775 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18Cl2N2O2 |
|---|
| Mol. Mass. | 353.243 |
|---|
| SMILES | COCCNC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
