Reaction Details |
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Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Ligand | BDBM50552287 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2034043 (CHEMBL4688201) |
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IC50 | 23180±n/a nM |
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Citation | Du, L; Wang, X; Cui, G; Xu, B Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors. Bioorg Med Chem29:0 (2021) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Type: | PROTEIN |
Mol. Mass.: | 18248.11 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1502595 |
Residue: | 163 |
Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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BDBM50552287 |
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n/a |
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Name | BDBM50552287 |
Synonyms: | CHEMBL4742117 |
Type | Small organic molecule |
Emp. Form. | C22H24N4O4S |
Mol. Mass. | 440.515 |
SMILES | CCO[C@@H]1CCN(C1)c1nc(NCC(O)=O)c(s1)C(=O)Nc1ccc2ccccc2c1 |r| |
Structure |
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