| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Ligand | BDBM50552303 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2034043 (CHEMBL4688201) |
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| IC50 | 7430±n/a nM |
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| Citation |  Du, L; Wang, X; Cui, G; Xu, B Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors. Bioorg Med Chem29:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18248.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502595 |
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| Residue: | 163 |
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| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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| BDBM50552303 |
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| n/a |
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| Name | BDBM50552303 |
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| Synonyms: | CHEMBL4797407 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N4O4S |
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| Mol. Mass. | 452.526 |
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| SMILES | OC1CC2CCC(C1)N2c1nc(NCC(O)=O)c(s1)C(=O)Nc1ccc2ccccc2c1 |
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| Structure | 
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