Reaction Details |
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Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Ligand | BDBM50552327 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2034044 (CHEMBL4688202) |
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Ki | 20±n/a nM |
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Citation | Du, L; Wang, X; Cui, G; Xu, B Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors. Bioorg Med Chem29:0 (2021) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Type: | PROTEIN |
Mol. Mass.: | 18248.11 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1502595 |
Residue: | 163 |
Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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BDBM50552327 |
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n/a |
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Name | BDBM50552327 |
Synonyms: | CHEMBL4751817 |
Type | Small organic molecule |
Emp. Form. | C39H50N7O11P |
Mol. Mass. | 823.8284 |
SMILES | C[C@H](OP(O)(O)=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N1CCCC[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCC(N)=O)C(N)=O |r| |
Structure |
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