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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Substance-K receptor | ||
| Ligand | BDBM50116647 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_209037 | ||
| Ki | 400±n/a nM | ||
| Citation |  Capozzi, G; Giannini, S; Menichetti, S; Nativi, C; Giolitti, A; Patacchini, R; Perrotta, E; Altamura, M; Alberto Maggi, C Design, synthesis and biological activity of carbohydrate-containing peptidomimetics as new ligands for the human tachykinin NK-2 receptor. Bioorg Med Chem Lett12:2263-6 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Substance-K receptor | |||
| Name: | Substance-K receptor | ||
| Synonyms: | NK-2 receptor | NK-2R | NK2R | NK2R_HUMAN | NKNAR | Neurokinin 2 receptor | Neurokinin A receptor | Neurokinin NK2 | Neurokinin-2 (NK-2) | Neuromedin-2 receptor (NK-2R) | SKR | TAC2R | TACR2 | Tachykinin receptor 2 | Tachykinin receptor 2 (NK2) | hnk-3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 44455.78 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21452 | ||
| Residue: | 398 | ||
| Sequence: |
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| BDBM50116647 | |||
| n/a | |||
| Name | BDBM50116647 | ||
| Synonyms: | 7,8-Bis-benzyloxy-6-benzyloxymethyl-3-methyl-1-oxo-6,7,8,8a-tetrahydro-1H,4aH-4,5-dioxa-1lambda*4*-thia-naphthalene-2-carboxylic acid phenyl ester | CHEMBL310084 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C37H34O8S | ||
| Mol. Mass. | 638.726 | ||
| SMILES | CC1=C(C(=O)Oc2ccccc2)S(=O)C2=C(OC(COCc3ccccc3)C(OCc3ccccc3)C2OCc2ccccc2)O1 |c:1,t:15,(14.45,-8.58,;14.03,-7.11,;13.14,-6.94,;12.07,-8.02,;10.57,-7.6,;12.44,-9.51,;11.37,-10.59,;11.74,-12.11,;10.64,-13.18,;9.17,-12.78,;8.77,-11.29,;9.87,-10.2,;12.77,-5.45,;11.27,-5.84,;13.54,-4.11,;14.73,-4.53,;13.96,-3.18,;12.32,-3.81,;12.32,-2.27,;13.63,-1.48,;13.63,.06,;14.97,.84,;14.97,2.38,;16.27,3.16,;17.63,2.38,;17.63,.84,;16.3,.07,;11.06,-3.39,;9.57,-2.98,;9.17,-1.48,;7.67,-1.08,;7.28,.41,;5.8,.81,;4.71,-.28,;5.1,-1.78,;6.6,-2.17,;11.81,-4.73,;10.27,-4.73,;8.73,-4.72,;7.39,-5.49,;6.06,-4.7,;4.73,-5.47,;4.71,-7.01,;6.06,-7.78,;7.39,-7.01,;15.13,-6.03,)| | ||
| Structure | 
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