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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Substance-K receptor | ||
| Ligand | BDBM50116651 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_209037 | ||
| Ki | 5010±n/a nM | ||
| Citation |  Capozzi, G; Giannini, S; Menichetti, S; Nativi, C; Giolitti, A; Patacchini, R; Perrotta, E; Altamura, M; Alberto Maggi, C Design, synthesis and biological activity of carbohydrate-containing peptidomimetics as new ligands for the human tachykinin NK-2 receptor. Bioorg Med Chem Lett12:2263-6 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Substance-K receptor | |||
| Name: | Substance-K receptor | ||
| Synonyms: | NK-2 receptor | NK-2R | NK2R | NK2R_HUMAN | NKNAR | Neurokinin 2 receptor | Neurokinin A receptor | Neurokinin NK2 | Neurokinin-2 (NK-2) | Neuromedin-2 receptor (NK-2R) | SKR | TAC2R | TACR2 | Tachykinin receptor 2 | Tachykinin receptor 2 (NK2) | hnk-3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 44455.78 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21452 | ||
| Residue: | 398 | ||
| Sequence: |
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| BDBM50116651 | |||
| n/a | |||
| Name | BDBM50116651 | ||
| Synonyms: | (7,8-Bis-benzyloxy-6-benzyloxymethyl-1,1-dioxo-3-phenyl-6,7,8,8a-tetrahydro-1H,4aH-4,5-dioxa-1lambda*6*-thia-naphthalen-2-yl)-phenyl-methanone | CHEMBL407769 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C42H38O8S | ||
| Mol. Mass. | 702.811 | ||
| SMILES | O=C(C1=C(OC2OC(COCc3ccccc3)C(OCc3ccccc3)C(OCc3ccccc3)C2S1(=O)=O)c1ccccc1)c1ccccc1 |t:2,(10.13,-8.76,;11.67,-8.75,;12.44,-7.4,;13.31,-7.59,;14.4,-6.51,;14.01,-5.02,;13.24,-3.67,;11.6,-4.29,;11.6,-2.75,;12.93,-1.97,;13.49,-.54,;15.01,-.29,;15.97,-1.5,;17.51,-1.27,;18.07,.16,;17.09,1.37,;15.57,1.14,;10.34,-3.87,;9.32,-2.74,;8.38,-1.49,;9.01,-.08,;10.55,.09,;11.16,1.49,;10.25,2.73,;8.71,2.56,;8.1,1.16,;11.11,-5.21,;9.57,-5.21,;8.24,-6,;6.89,-5.23,;6.89,-3.69,;5.56,-2.95,;4.23,-3.72,;4.25,-5.26,;5.58,-6.03,;12.82,-4.6,;12.05,-5.93,;11.28,-7.26,;10.51,-5.93,;14.8,-7.99,;15.17,-9.47,;16.67,-9.87,;17.74,-8.78,;17.34,-7.29,;15.87,-6.91,;12.44,-10.08,;11.67,-11.42,;12.44,-12.75,;13.98,-12.74,;14.75,-11.39,;13.98,-10.06,)| | ||
| Structure | 
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