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Reaction Details
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TargetSigma intracellular receptor 2
LigandBDBM50559177
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2068272 (CHEMBL4723525)
Ki 125±n/a nM
Citation Ye, NQin, WTian, SXu, QWold, EAZhou, JZhen, XC Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases. J Med Chem63:15187-15217 (2020) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma intracellular receptor 2
Name:Sigma intracellular receptor 2
Synonyms:S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:Protein
Mol. Mass.:20953.88
Organism:Rattus norvegicus (Rat)
Description:Q5U3Y7
Residue:176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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BDBM50559177
n/a
NameBDBM50559177
Synonyms:CHEMBL4760592
TypeSmall organic molecule
Emp. Form.C24H31N
Mol. Mass.333.5096
SMILESC(C1CCCCC1)N1CCC(Cc2ccccc2)c2ccccc2C1
Structure
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