| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50559182 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2068289 (CHEMBL4723542) |
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| Ki | >854±n/a nM |
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| Citation |  Ye, N; Qin, W; Tian, S; Xu, Q; Wold, EA; Zhou, J; Zhen, XC Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases. J Med Chem63:15187-15217 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20953.88 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5U3Y7 |
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| Residue: | 176 |
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| Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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| BDBM50559182 |
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| n/a |
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| Name | BDBM50559182 |
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| Synonyms: | CHEMBL4744344 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24FNO |
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| Mol. Mass. | 313.4091 |
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| SMILES | Cc1ccc(CN2CCC(CC2)C(O)c2ccc(F)cc2)cc1 |
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| Structure | 
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