| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM15581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2068299 (CHEMBL4723552) |
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| Ki | 505±n/a nM |
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| Citation |  Ye, N; Qin, W; Tian, S; Xu, Q; Wold, EA; Zhou, J; Zhen, XC Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases. J Med Chem63:15187-15217 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | S2r | SGMR2_MOUSE | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
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| Type: | n/a |
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| Mol. Mass.: | 20818.69 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q8VD00 |
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| Residue: | 176 |
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| Sequence: | MGALAARRCVEWLLGLYFVSHIPITLFIDLQAVLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLLCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAAHTITTLIPILYTLLF
EDFSKAVAFKGQRPESFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKYEEKRKKK
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| BDBM15581 |
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| n/a |
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| Name | BDBM15581 |
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| Synonyms: | CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine | US8633208, Clorgyline | US9603833, Clorgyline | [3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15Cl2NO |
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| Mol. Mass. | 272.17 |
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| SMILES | CN(CCCOc1ccc(Cl)cc1Cl)CC#C |
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| Structure | 
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