| Reaction Details |
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 | Report a problem with these data |
| Target | Transient receptor potential cation channel subfamily V member 4 |
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| Ligand | BDBM50426575 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2071468 (CHEMBL4727002) |
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| IC50 | 5900±n/a nM |
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| Citation |  Liu, N; Yan, F; Ma, Q; Zhao, J Modulation of TRPV4 and BKCa for treatment of brain diseases. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transient receptor potential cation channel subfamily V member 4 |
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| Name: | Transient receptor potential cation channel subfamily V member 4 |
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| Synonyms: | TRPV4_MOUSE | Trp12 | Trpv4 | Vrl2 | Vroac |
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| Type: | PROTEIN |
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| Mol. Mass.: | 98032.61 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1514430 |
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| Residue: | 871 |
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| Sequence: | MADPGDGPRAAPGEVAEPPGDESGTSGGEAFPLSSLANLFEGEEGSSSLSPVDASRPAGP
GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHPSDN
KRWRRKVVEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLSFLLTHKKRL
TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT
SLHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI
VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCSRLFPDS
NLETVLNNDGLSPLMMAAKTGKIGVFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYD
LSSLDTCGEEVSVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLC
AMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTSIKDLFTKKCPGV
NSLFVDGSFQLLYFIYSVLVVVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTG
TYSIMIQKILFKDLFRFLLVYLLFMIGYASALVTLLNPCTNMKVCDEDQSNCTVPTYPAC
RDSETFSAFLLDLFKLTIGMGDLEMLSSAKYPVVFILLLVTYIILTFVLLLNMLIALMGE
TVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRV
DEVNWSHWNQNLGIINEDPGKSEIYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSSADE
VVVPLDNLGNPNCDGHQQGYAPKWRTDDAPL
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| BDBM50426575 |
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| n/a |
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| Name | BDBM50426575 |
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| Synonyms: | CHEMBL2324347 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22Cl2N2O2S |
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| Mol. Mass. | 353.308 |
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| SMILES | CC(C)NCCN(C(C)C)S(=O)(=O)c1ccc(Cl)cc1Cl |
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| Structure | 
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