| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arginase-2, mitochondrial |
|---|
| Ligand | BDBM50230418 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2074194 (CHEMBL4729728) |
|---|
| Ki | 1600±n/a nM |
|---|
| Citation |  Borek, B; Gajda, T; Golebiowski, A; Blaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem28:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arginase-2, mitochondrial |
|---|
| Name: | Arginase-2, mitochondrial |
|---|
| Synonyms: | ARG2 | ARGI2_HUMAN | Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38576.93 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_978892 |
|---|
| Residue: | 354 |
|---|
| Sequence: | MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
|
|
|
|---|
| BDBM50230418 |
|---|
| n/a |
|---|
| Name | BDBM50230418 |
|---|
| Synonyms: | CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-arginine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H14N4O3 |
|---|
| Mol. Mass. | 190.2004 |
|---|
| SMILES | NC(NO)=NCCC[C@H]([NH3+])C([O-])=O |r,w:4.4| |
|---|
| Structure | 
|
|---|
Search and Browse
