| Reaction Details |
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 | Report a problem with these data |
| Target | Mucolipin-1 |
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| Ligand | BDBM50569847 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2110657 (CHEMBL4819507) |
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| IC50 | 2300±n/a nM |
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| Citation |  Leser, C; Keller, M; Gerndt, S; Urban, N; Chen, CC; Schaefer, M; Grimm, C; Bracher, F Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3. Eur J Med Chem210:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mucolipin-1 |
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| Name: | Mucolipin-1 |
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| Synonyms: | MCLN1_HUMAN | MCOLN1 | MG-2 | ML1 | ML4 | Mucolipidin | TRPML1 | Transient receptor potential channel mucolipin 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 65027.60 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119757 |
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| Residue: | 580 |
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| Sequence: | MTAPAGPRGSETERLLTPNPGYGTQAGPSPAPPTPPEEEDLRRRLKYFFMSPCDKFRAKG
RKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAAY
TREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPAND
TFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTI
NLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRLL
FDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEFVNGWYILLVT
SDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRV
ALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAM
QAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAY
IAQCQDSPTSGKFRRGSGSACSLLCCCGRDPSEEHSLLVN
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| BDBM50569847 |
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| n/a |
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| Name | BDBM50569847 |
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| Synonyms: | CHEMBL4847300 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29N3O3S2 |
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| Mol. Mass. | 435.603 |
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| SMILES | COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1cccs1 |r| |
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| Structure | 
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