| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 8 |
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| Ligand | BDBM50138422 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_88029 |
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| IC50 | 780.0±n/a nM |
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| Citation |  Wu, TY; Hassig, C; Wu, Y; Ding, S; Schultz, PG Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group. Bioorg Med Chem Lett14:449-53 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 8 |
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| Name: | Histone deacetylase 8 |
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| Synonyms: | HD8 | HDAC8 | HDAC8_HUMAN | HDACL1 | Histone deacetylase 8 (HDAC-8) | Human HDAC8 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41749.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9BY41 |
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| Residue: | 377 |
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| Sequence: | MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
RIQQILNYIKGNLKHVV
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| BDBM50138422 |
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| n/a |
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| Name | BDBM50138422 |
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| Synonyms: | 8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-2-ylamide | CHEMBL141909 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N2O3 |
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| Mol. Mass. | 328.4055 |
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| SMILES | ON(CCCCCCCC(=O)Nc1ccc2ccccc2c1)C=O |
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| Structure | 
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