| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 2b |
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| Ligand | BDBM50139930 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_87549 (CHEMBL695147) |
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| IC50 | 200±n/a nM |
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| Citation |  Mai, A; Massa, S; Cerbara, I; Valente, S; Ragno, R; Bottoni, P; Scatena, R; Loidl, P; Brosch, G 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity. J Med Chem47:1098-109 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 2b |
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| Name: | Histone deacetylase 2b |
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| Synonyms: | Histone deacetylase HD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30785.07 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_87549 |
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| Residue: | 286 |
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| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
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| BDBM50139930 |
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| n/a |
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| Name | BDBM50139930 |
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| Synonyms: | CHEMBL269230 | N,N'-Dihydroxy-2-(1-methyl-4-phenylacetyl-1H-pyrrol-2-ylmethylene)-malonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17N3O5 |
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| Mol. Mass. | 343.334 |
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| SMILES | [#6]-n1cc(cc1\[#6]=[#6](\[#6](=O)-[#7]-[#8])-[#6](=O)-[#7]-[#8])-[#6](=O)-[#6]-c1ccccc1 |
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| Structure | 
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