Compile Data Set for Download or QSAR

Found 141 hits with Last Name = 'cerbara' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50026872 (CHEMBL1233506 | SC-74020) Show SMILES CCCCCc1ccc(cc1)C(=O)Nc1ccc(cc1)S(=O)(=O)N(CCN1CCOCC1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C29H42N4O6S/c1-4-5-6-7-23-8-10-24(11-9-23)28(34)30-25-12-14-26(15-13-25)40(37,38)33(27(22(2)3)29(35)31-36)17-16-32-18-20-39-21-19-32/h8-15,22,27,36H,4-7,16-21H2,1-3H3,(H,30,34)(H,31,35)/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50366175 (CHEMBL1957606) Show SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O7S2/c17-11-1-3-12(4-2-11)26-13-5-7-14(8-6-13)28(24,25)19-10-27(22,23)9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50366175 (CHEMBL1957606) Show SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O7S2/c17-11-1-3-12(4-2-11)26-13-5-7-14(8-6-13)28(24,25)19-10-27(22,23)9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50366203 (CHEMBL1957601) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)N2CSC[C@H]2C(=O)NO)cc1 |r| Show InChI InChI=1S/C17H18N2O6S2/c1-24-12-2-4-13(5-3-12)25-14-6-8-15(9-7-14)27(22,23)19-11-26-10-16(19)17(20)18-21/h2-9,16,21H,10-11H2,1H3,(H,18,20)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50366175 (CHEMBL1957606) Show SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O7S2/c17-11-1-3-12(4-2-11)26-13-5-7-14(8-6-13)28(24,25)19-10-27(22,23)9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50366205 (CHEMBL1957603) Show SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C16H15FN2O5S2/c17-11-1-3-12(4-2-11)24-13-5-7-14(8-6-13)26(22,23)19-10-25-9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50366175 (CHEMBL1957606) Show SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O7S2/c17-11-1-3-12(4-2-11)26-13-5-7-14(8-6-13)28(24,25)19-10-27(22,23)9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50366173 (CHEMBL1957604) Show SMILES ONC(=O)[C@@H]1CS(=O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C16H16N2O5S2/c19-16(17-20)15-10-24(21)11-18(15)25(22,23)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9,15,20H,10-11H2,(H,17,19)/t15-,24?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50366203 (CHEMBL1957601) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)N2CSC[C@H]2C(=O)NO)cc1 |r| Show InChI InChI=1S/C17H18N2O6S2/c1-24-12-2-4-13(5-3-12)25-14-6-8-15(9-7-14)27(22,23)19-11-26-10-16(19)17(20)18-21/h2-9,16,21H,10-11H2,1H3,(H,18,20)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50134805 (6,9-Dibenzyl-12-(6-oxiranyl-6-oxo-hexyl)-decahydro...) Show SMILES O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O)C1CO1 Show InChI InChI=1S/C34H42N4O6/c39-29(30-22-44-30)18-9-3-8-16-25-31(40)36-26(20-23-12-4-1-5-13-23)32(41)37-27(21-24-14-6-2-7-15-24)34(43)38-19-11-10-17-28(38)33(42)35-25/h1-2,4-7,12-15,25-28,30H,3,8-11,16-22H2,(H,35,42)(H,36,40)(H,37,41)/t25-,26-,27-,28+,30?/m0/s1	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50366205 (CHEMBL1957603) Show SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C16H15FN2O5S2/c17-11-1-3-12(4-2-11)24-13-5-7-14(8-6-13)26(22,23)19-10-25-9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50366204 (CHEMBL1957602) Show SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O5S2/c17-11-1-3-12(4-2-11)24-13-5-7-14(8-6-13)26(22,23)19-10-25-9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50366204 (CHEMBL1957602) Show SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O5S2/c17-11-1-3-12(4-2-11)24-13-5-7-14(8-6-13)26(22,23)19-10-25-9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50366175 (CHEMBL1957606) Show SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O7S2/c17-11-1-3-12(4-2-11)26-13-5-7-14(8-6-13)28(24,25)19-10-27(22,23)9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP12 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139952 (CHEMBL268286 | N-Hydroxy-3-[1-methyl-4-(3-phenyl-p...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCc1ccccc1 |w:7.8| Show InChI InChI=1S/C17H18N2O3/c1-19-12-14(11-15(19)8-10-17(21)18-22)16(20)9-7-13-5-3-2-4-6-13/h2-6,8,10-12,22H,7,9H2,1H3,(H,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139952 (CHEMBL268286 | N-Hydroxy-3-[1-methyl-4-(3-phenyl-p...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCc1ccccc1 |w:7.8| Show InChI InChI=1S/C17H18N2O3/c1-19-12-14(11-15(19)8-10-17(21)18-22)16(20)9-7-13-5-3-2-4-6-13/h2-6,8,10-12,22H,7,9H2,1H3,(H,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140882 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)cc1C(=O)c1ccccc1 Show InChI InChI=1S/C15H14N2O3/c1-17-10-11(7-8-14(18)16-20)9-13(17)15(19)12-5-3-2-4-6-12/h2-10,20H,1H3,(H,16,18)/b8-7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140882 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)cc1C(=O)c1ccccc1 Show InChI InChI=1S/C15H14N2O3/c1-17-10-11(7-8-14(18)16-20)9-13(17)15(19)12-5-3-2-4-6-12/h2-10,20H,1H3,(H,16,18)/b8-7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50366174 (CHEMBL1957605) Show SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C16H16N2O6S2/c19-16(17-20)15-10-25(21,22)11-18(15)26(23,24)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9,15,20H,10-11H2,(H,17,19)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139949 (CHEMBL13200 | N-Hydroxy-3-[1-methyl-4-(6-phenyl-he...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C20H24N2O3/c1-22-15-17(14-18(22)12-13-20(24)21-25)19(23)11-7-3-6-10-16-8-4-2-5-9-16/h2,4-5,8-9,12-15,25H,3,6-7,10-11H2,1H3,(H,21,24)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139949 (CHEMBL13200 | N-Hydroxy-3-[1-methyl-4-(6-phenyl-he...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C20H24N2O3/c1-22-15-17(14-18(22)12-13-20(24)21-25)19(23)11-7-3-6-10-16-8-4-2-5-9-16/h2,4-5,8-9,12-15,25H,3,6-7,10-11H2,1H3,(H,21,24)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50135752 ((2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyr...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)Cc1ccccc1 |w:7.8| Show InChI InChI=1S/C16H16N2O3/c1-18-11-13(10-14(18)7-8-16(20)17-21)15(19)9-12-5-3-2-4-6-12/h2-8,10-11,21H,9H2,1H3,(H,17,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139935 (CHEMBL12927 | N-Hydroxy-3-[1-methyl-4-(1-phenyl-cy...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)C1(CC1)c1ccccc1 Show InChI InChI=1S/C18H18N2O3/c1-20-12-13(11-15(20)7-8-16(21)19-23)17(22)18(9-10-18)14-5-3-2-4-6-14/h2-8,11-12,23H,9-10H2,1H3,(H,19,21)/b8-7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50366174 (CHEMBL1957605) Show SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C16H16N2O6S2/c19-16(17-20)15-10-25(21,22)11-18(15)26(23,24)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9,15,20H,10-11H2,(H,17,19)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50135752 ((2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyr...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)Cc1ccccc1 |w:7.8| Show InChI InChI=1S/C16H16N2O3/c1-18-11-13(10-14(18)7-8-16(20)17-21)15(19)9-12-5-3-2-4-6-12/h2-8,10-11,21H,9H2,1H3,(H,17,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139935 (CHEMBL12927 | N-Hydroxy-3-[1-methyl-4-(1-phenyl-cy...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)C1(CC1)c1ccccc1 Show InChI InChI=1S/C18H18N2O3/c1-20-12-13(11-15(20)7-8-16(21)19-23)17(22)18(9-10-18)14-5-3-2-4-6-14/h2-8,11-12,23H,9-10H2,1H3,(H,19,21)/b8-7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139942 ((5S,8S,11S)-5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexy...) Show SMILES C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](CCCCCC(=O)C2CO2)NC(=O)CCCCCNC1=O Show InChI InChI=1S/C22H36N4O6/c1-14-20(29)23-12-8-4-7-11-19(28)26-16(22(31)25-15(2)21(30)24-14)9-5-3-6-10-17(27)18-13-32-18/h14-16,18H,3-13H2,1-2H3,(H,23,29)(H,24,30)(H,25,31)(H,26,28)/t14-,15-,16-,18?/m0/s1	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139937 (CHEMBL274906 | N-Hydroxy-3-[1-methyl-4-(5-phenyl-p...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C19H22N2O3/c1-21-14-16(13-17(21)11-12-19(23)20-24)18(22)10-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,11-14,24H,5-6,9-10H2,1H3,(H,20,23)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139937 (CHEMBL274906 | N-Hydroxy-3-[1-methyl-4-(5-phenyl-p...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C19H22N2O3/c1-21-14-16(13-17(21)11-12-19(23)20-24)18(22)10-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,11-14,24H,5-6,9-10H2,1H3,(H,20,23)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 2b (Zea mays)	BDBM50139945 (CHEMBL273731 | N-Hydroxy-3-[1-methyl-4-(naphthalen...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H16N2O3/c1-21-12-16(11-17(21)8-9-18(22)20-24)19(23)15-7-6-13-4-2-3-5-14(13)10-15/h2-12,24H,1H3,(H,20,22)/b9-8+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139945 (CHEMBL273731 | N-Hydroxy-3-[1-methyl-4-(naphthalen...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H16N2O3/c1-21-12-16(11-17(21)8-9-18(22)20-24)19(23)15-7-6-13-4-2-3-5-14(13)10-15/h2-12,24H,1H3,(H,20,22)/b9-8+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139947 (CHEMBL265077 | N-Hydroxy-3-[1-methyl-4-(4-phenyl-b...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C18H20N2O3/c1-20-13-15(12-16(20)10-11-18(22)19-23)17(21)9-5-8-14-6-3-2-4-7-14/h2-4,6-7,10-13,23H,5,8-9H2,1H3,(H,19,22)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139947 (CHEMBL265077 | N-Hydroxy-3-[1-methyl-4-(4-phenyl-b...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C18H20N2O3/c1-20-13-15(12-16(20)10-11-18(22)19-23)17(21)9-5-8-14-6-3-2-4-7-14/h2-4,6-7,10-13,23H,5,8-9H2,1H3,(H,19,22)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139944 (CHEMBL12890 | N-Hydroxy-3-[1-methyl-4-(naphthalene...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H16N2O3/c1-21-12-14(11-15(21)9-10-18(22)20-24)19(23)17-8-4-6-13-5-2-3-7-16(13)17/h2-12,24H,1H3,(H,20,22)/b10-9+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139944 (CHEMBL12890 | N-Hydroxy-3-[1-methyl-4-(naphthalene...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H16N2O3/c1-21-12-14(11-15(21)9-10-18(22)20-24)19(23)17-8-4-6-13-5-2-3-7-16(13)17/h2-12,24H,1H3,(H,20,22)/b10-9+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50366173 (CHEMBL1957604) Show SMILES ONC(=O)[C@@H]1CS(=O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C16H16N2O5S2/c19-16(17-20)15-10-24(21)11-18(15)25(22,23)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9,15,20H,10-11H2,(H,17,19)/t15-,24?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50366204 (CHEMBL1957602) Show SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C16H15ClN2O5S2/c17-11-1-3-12(4-2-11)24-13-5-7-14(8-6-13)26(22,23)19-10-25-9-15(19)16(20)18-21/h1-8,15,21H,9-10H2,(H,18,20)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139930 (CHEMBL269230 | N,N'-Dihydroxy-2-(1-methyl-4-phenyl...) Show SMILES [#6]-n1cc(cc1\[#6]=[#6](\[#6](=O)-[#7]-[#8])-[#6](=O)-[#7]-[#8])-[#6](=O)-[#6]-c1ccccc1 Show InChI InChI=1S/C17H17N3O5/c1-20-10-12(15(21)7-11-5-3-2-4-6-11)8-13(20)9-14(16(22)18-24)17(23)19-25/h2-6,8-10,24-25H,7H2,1H3,(H,18,22)(H,19,23)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50366200 (CHEMBL1957598) Show SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C16H16N2O4S2/c19-16(17-20)15-10-23-11-18(15)24(21,22)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9,15,20H,10-11H2,(H,17,19)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl) Curated by ChEMBL					Assay Description Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...				Bioorg Med Chem 20: 2323-37 (2012) Article DOI: 10.1016/j.bmc.2012.02.010 BindingDB Entry DOI: 10.7270/Q2N29XD5
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139930 (CHEMBL269230 | N,N'-Dihydroxy-2-(1-methyl-4-phenyl...) Show SMILES [#6]-n1cc(cc1\[#6]=[#6](\[#6](=O)-[#7]-[#8])-[#6](=O)-[#7]-[#8])-[#6](=O)-[#6]-c1ccccc1 Show InChI InChI=1S/C17H17N3O5/c1-20-10-12(15(21)7-11-5-3-2-4-6-11)8-13(20)9-14(16(22)18-24)17(23)19-25/h2-6,8-10,24-25H,7H2,1H3,(H,18,22)(H,19,23)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139951 (CHEMBL273454 | N-Hydroxy-3-[1-methyl-4-(8-phenyl-o...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCCCCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C22H28N2O3/c1-24-17-19(16-20(24)14-15-22(26)23-27)21(25)13-9-4-2-3-6-10-18-11-7-5-8-12-18/h5,7-8,11-12,14-17,27H,2-4,6,9-10,13H2,1H3,(H,23,26)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139951 (CHEMBL273454 | N-Hydroxy-3-[1-methyl-4-(8-phenyl-o...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)CCCCCCCc1ccccc1 |w:7.8| Show InChI InChI=1S/C22H28N2O3/c1-24-17-19(16-20(24)14-15-22(26)23-27)21(25)13-9-4-2-3-6-10-18-11-7-5-8-12-18/h5,7-8,11-12,14-17,27H,2-4,6,9-10,13H2,1H3,(H,23,26)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair

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