| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Monoacylglycerol lipase ABHD6 |
|---|
| Ligand | BDBM50577909 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2131323 (CHEMBL4840838) |
|---|
| IC50 | 39800±n/a nM |
|---|
| Citation |  Schafroth, MA; Mazzoccanti, G; Reynoso-Moreno, I; Erni, R; Pollastro, F; Caprioglio, D; Botta, B; Allegrone, G; Grassi, G; Chicca, A; Gasparrini, F; Gertsch, J; Carreira, EM; Appendino, G ? J Nat Prod84:2502-2510 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Monoacylglycerol lipase ABHD6 |
|---|
| Name: | Monoacylglycerol lipase ABHD6 |
|---|
| Synonyms: | 2-arachidonoylglycerol hydrolase | ABHD6 | ABHD6_HUMAN | Abhydrolase domain-containing protein 6 | Monoacylglycerol lipase ABHD6 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38341.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_105457 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQF
CYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLS
IDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYST
DNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHN
NFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVEL
LENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD
|
|
|
|---|
| BDBM50577909 |
|---|
| n/a |
|---|
| Name | BDBM50577909 |
|---|
| Synonyms: | CHEMBL4845760 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H30O2 |
|---|
| Mol. Mass. | 314.4617 |
|---|
| SMILES | [H][C@@]12C=C(C)CC[C@]1([H])C(C)(C)Oc1cc(CCCCC)cc(O)c21 |r,t:2| |
|---|
| Structure | 
|
|---|
Search and Browse
