| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50148119 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86908 (CHEMBL698418) |
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| Ki | 108±n/a nM |
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| Citation |  Pelloux-Léon, N; Fkyerat, A; Piripitsi, A; Tertiuk, W; Schunack, W; Stark, H; Garbarg, M; Ligneau, X; Arrang, JM; Schwartz, JC; Ganellin, CR Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain. J Med Chem47:3264-74 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50148119 |
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| n/a |
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| Name | BDBM50148119 |
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| Synonyms: | 3-[3-(1H-Imidazol-4-yl)-propoxy]-benzonitrile | CHEMBL110582 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13N3O |
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| Mol. Mass. | 227.2618 |
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| SMILES | N#Cc1cccc(OCCCc2cnc[nH]2)c1 |
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| Structure | 
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