| Reaction Details |
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 | Report a problem with these data |
| Target | C-type lectin domain family 4 member M |
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| Ligand | BDBM50509063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2149161 (CHEMBL5033559) |
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| IC50 | 26800±n/a nM |
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| Citation |  Chakroun, K; Taouai, M; Porkolab, V; Luczkowiak, J; Sommer, R; Cheneau, C; Mathiron, D; Ben Maaouia, MA; Pilard, S; Abidi, R; Mullié, C; Fieschi, F; Cragg, PJ; Halary, F; Delgado, R; Benazza, M Low-Valent Calix[4]arene Glycoconjugates Based on Hydroxamic Acid Bearing Linkers as Potent Inhibitors in a Model of Ebola Virus Cis-Infection and HCMV-gB-Recombinant Glycoprotein Interaction with MDDC Cells by Blocking DC-SIGN. J Med Chem64:14332-14343 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-type lectin domain family 4 member M |
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| Name: | C-type lectin domain family 4 member M |
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| Synonyms: | CD209 antigen-like protein 1 | CD209L | CD209L1 | CD299 | CD_antigen=CD299 | CLC4M_HUMAN | CLEC4M | DC-SIGN-related protein | DC-SIGN2 | DC-SIGNR | Dendritic cell-specific ICAM-3-grabbing non-integrin 2 | L-SIGN | Liver/lymph node-specific ICAM-3-grabbing non-integrin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45339.05 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105433 |
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| Residue: | 399 |
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| Sequence: | MSDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGHGALVLQLLSFML
LAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLK
AAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQE
IYQELTRLKAAVGELPEKSKLQEIYQELTELKAAVGELPEKSKLQEIYQELTQLKAAVGE
LPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVR
AQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEP
NNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAACFRDE
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| BDBM50509063 |
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| n/a |
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| Name | BDBM50509063 |
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| Synonyms: | CHEMBL4515649 |
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| Type | Small organic molecule |
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| Emp. Form. | C128H188N28O32 |
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| Mol. Mass. | 2631.0307 |
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| SMILES | C[C@@H]1O[C@@H](OCc2cn(CCCCCC(=O)N(O)Cc3cn(CCCOc4c5Cc6cc(cc(Cc7cc(cc(Cc8cc(cc(Cc4cc(c5)C(C)(C)C)c8OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]8O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]8O)nn5)nn4)C(C)(C)C)c7OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]7O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]7O)nn5)nn4)C(C)(C)C)c6OCCCn4cc(CN(O)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn4)C(C)(C)C)nn3)nn2)[C@@H](O)[C@H](O)[C@@H]1O |r| |
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| Structure | 
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