| Reaction Details |
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 | Report a problem with these data |
| Target | C-type lectin domain family 4 member M |
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| Ligand | BDBM50580864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2149165 (CHEMBL5033563) |
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| IC50 | 602±n/a nM |
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| Citation |  Chakroun, K; Taouai, M; Porkolab, V; Luczkowiak, J; Sommer, R; Cheneau, C; Mathiron, D; Ben Maaouia, MA; Pilard, S; Abidi, R; Mullié, C; Fieschi, F; Cragg, PJ; Halary, F; Delgado, R; Benazza, M Low-Valent Calix[4]arene Glycoconjugates Based on Hydroxamic Acid Bearing Linkers as Potent Inhibitors in a Model of Ebola Virus Cis-Infection and HCMV-gB-Recombinant Glycoprotein Interaction with MDDC Cells by Blocking DC-SIGN. J Med Chem64:14332-14343 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-type lectin domain family 4 member M |
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| Name: | C-type lectin domain family 4 member M |
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| Synonyms: | CD209 antigen-like protein 1 | CD209L | CD209L1 | CD299 | CD_antigen=CD299 | CLC4M_HUMAN | CLEC4M | DC-SIGN-related protein | DC-SIGN2 | DC-SIGNR | Dendritic cell-specific ICAM-3-grabbing non-integrin 2 | L-SIGN | Liver/lymph node-specific ICAM-3-grabbing non-integrin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45339.05 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105433 |
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| Residue: | 399 |
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| Sequence: | MSDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGHGALVLQLLSFML
LAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLK
AAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQE
IYQELTRLKAAVGELPEKSKLQEIYQELTELKAAVGELPEKSKLQEIYQELTQLKAAVGE
LPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVR
AQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEP
NNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAACFRDE
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| BDBM50580864 |
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| n/a |
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| Name | BDBM50580864 |
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| Synonyms: | CHEMBL5077032 |
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| Type | Small organic molecule |
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| Emp. Form. | C144H208N32O40S4 |
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| Mol. Mass. | 3155.643 |
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| SMILES | COC(=O)CNC(=O)CN(Cc1cn(CCCOc2c3cc(cc2sc2cc(cc(sc4cc(cc(sc5cc(cc(s3)c5OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn5cc(CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)nn5)nn3)C(C)(C)C)c4OCCCn3cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn4cc(CO[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]5O)nn4)nn3)C(C)(C)C)c2OCCCn2cc(CN(CC(=O)NCC(=O)OC)C(=O)CCCCCn3cc(CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)nn3)nn2)C(C)(C)C)C(C)(C)C)nn1)C(=O)CCCCCn1cc(CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)nn1 |r| |
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| Structure | 
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