Citation | Chen, C; Wilcoxen, KM; Huang, CQ; Xie, YF; McCarthy, JR; Webb, TR; Zhu, YF; Saunders, J; Liu, XJ; Chen, TK; Bozigian, H; Grigoriadis, DE Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists. J Med Chem47:4787-98 (2004) [PubMed] Article |
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SMILES | CC(C)C(C)Nc1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(6.4,3.7,;4.9,4.03,;4.42,5.48,;3.88,2.86,;2.37,3.17,;4.36,1.4,;3.34,.25,;3.81,-1.2,;2.79,-2.36,;3.28,-3.81,;1.29,-2.04,;.8,-.58,;-.6,.04,;-.44,1.58,;-1.6,2.59,;1.06,1.91,;1.83,.56,;-1.93,-.73,;-1.93,-2.29,;-3.26,-3.06,;-4.59,-2.29,;-4.59,-.75,;-3.26,.04,;-3.27,1.58,;-5.93,-3.06,;-5.93,-4.6,;-7.27,-2.29,)| |