Citation | Chen, C; Wilcoxen, KM; Huang, CQ; Xie, YF; McCarthy, JR; Webb, TR; Zhu, YF; Saunders, J; Liu, XJ; Chen, TK; Bozigian, H; Grigoriadis, DE Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists. J Med Chem47:4787-98 (2004) [PubMed] Article |
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SMILES | CCCCN(CCCC)c1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(8.52,2.82,;7.49,1.66,;5.98,1.98,;4.95,.83,;3.45,1.14,;2.97,2.59,;3.97,3.75,;3.51,5.2,;4.53,6.39,;2.43,-.02,;2.9,-1.47,;1.87,-2.62,;2.36,-4.08,;.38,-2.31,;-.11,-.85,;-1.51,-.23,;-1.35,1.31,;-2.51,2.33,;.15,1.63,;.92,.3,;-2.84,-1,;-2.84,-2.55,;-4.17,-3.32,;-5.5,-2.55,;-5.5,-1.01,;-4.17,-.23,;-4.18,1.31,;-6.84,-3.32,;-6.84,-4.86,;-8.17,-2.55,)| |