| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
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| Ligand | BDBM50152516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303667 (CHEMBL830428) |
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| Ki | 780.0±n/a nM |
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| Citation |  Torisu, K; Kobayashi, K; Iwahashi, M; Nakai, Y; Onoda, T; Nagase, T; Sugimoto, I; Okada, Y; Matsumoto, R; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett14:4891-5 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP1 subtype |
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| Name: | Prostaglandin E2 receptor EP1 subtype |
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| Synonyms: | PE2R1_MOUSE | PGE receptor, EP1 subtype | Prostaglandin E1 | Prostaglandin E2 receptor EP1 subtype | Prostanoid EP1 receptor | Ptger1 | Ptgerep1 |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 43000.62 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 405 |
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| Sequence: | MSPCGLNLSLADEAATCATPRLPNTSVVLPTGDNGTSPALPIFSMTLGAVSNVLALALLA
QVAGRMRRRRSAATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMV
FFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGR
YELQYPGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRR
SRRFRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRVHAHDVEMVG
QLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQA
MLRQLLRLLPLRVSAKGGPTELGLTKSAWEASSLRSSRHSGFSHL
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| BDBM50152516 |
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| n/a |
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| Name | BDBM50152516 |
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| Synonyms: | CHEMBL184684 | {1-[4-(Benzo[1,3]dioxol-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C26H21NO6 |
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| Mol. Mass. | 443.448 |
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| SMILES | Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2Oc3ccccc3O2)cc1 |
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| Structure | 
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