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Compile Data Set for Download or QSAR

Found 592 hits with Last Name = 'sugimoto' and Initial = 'i'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315980
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1cccc(c1)C#N
Show InChI InChI=1S/C32H28N4O4S/c33-22-25-5-3-8-30(20-25)41(38,39)35-32(37)14-13-28-12-10-26(23-36-17-4-16-34-36)21-31(28)40-18-15-24-9-11-27-6-1-2-7-29(27)19-24/h1-12,16-17,19-21H,13-15,18,23H2,(H,35,37)
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 0.0650n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315979
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C31H27F2N3O4S/c32-28-12-11-27(20-29(28)33)41(38,39)35-31(37)13-10-25-9-7-23(21-36-16-3-15-34-36)19-30(25)40-17-14-22-6-8-24-4-1-2-5-26(24)18-22/h1-9,11-12,15-16,18-20H,10,13-14,17,21H2,(H,35,37)
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 0.0860n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315985
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(methyl(phenyl...)
Show SMILES CN(CCOc1cc(Cn2cccn2)ccc1CCC(=O)NS(=O)(=O)c1ccc(F)c(F)c1)c1ccccc1
Show InChI InChI=1S/C28H28F2N4O4S/c1-33(23-6-3-2-4-7-23)16-17-38-27-18-21(20-34-15-5-14-31-34)8-9-22(27)10-13-28(35)32-39(36,37)24-11-12-25(29)26(30)19-24/h2-9,11-12,14-15,18-19H,10,13,16-17,20H2,1H3,(H,32,35)
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 0.120n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315981
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(naphthalen-1-ylm...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1ONCc1cccc2ccccc12
Show InChI InChI=1S/C30H26F2N4O4S/c31-27-13-12-25(18-28(27)32)41(38,39)35-30(37)14-11-23-10-9-21(20-36-16-4-15-33-36)17-29(23)40-34-19-24-7-3-6-22-5-1-2-8-26(22)24/h1-10,12-13,15-18,34H,11,14,19-20H2,(H,35,37)
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 0.130n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315967
PNG
(CHEMBL1092432 | N-(3,4-difluorophenylsulfonyl)-3-(...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccnc2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C33H28F2N2O5S/c34-30-13-12-29(20-31(30)35)43(39,40)37-33(38)14-11-26-10-8-24(22-42-28-6-3-16-36-21-28)19-32(26)41-17-15-23-7-9-25-4-1-2-5-27(25)18-23/h1-10,12-13,16,18-21H,11,14-15,17,22H2,(H,37,38)
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 0.160n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315982
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccccc1
Show InChI InChI=1S/C27H25F2N3O4S/c28-24-11-10-23(18-25(24)29)37(34,35)31-27(33)12-9-22-8-7-21(19-32-15-4-14-30-32)17-26(22)36-16-13-20-5-2-1-3-6-20/h1-8,10-11,14-15,17-18H,9,12-13,16,19H2,(H,31,33)
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 0.200n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315978
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C31H27ClFN3O4S/c32-28-20-27(11-12-29(28)33)41(38,39)35-31(37)13-10-25-9-7-23(21-36-16-3-15-34-36)19-30(25)40-17-14-22-6-8-24-4-1-2-5-26(24)18-22/h1-9,11-12,15-16,18-20H,10,13-14,17,21H2,(H,35,37)
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 0.220n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315984
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCOc1ccccc1
Show InChI InChI=1S/C27H25F2N3O5S/c28-24-11-10-23(18-25(24)29)38(34,35)31-27(33)12-9-21-8-7-20(19-32-14-4-13-30-32)17-26(21)37-16-15-36-22-5-2-1-3-6-22/h1-8,10-11,13-14,17-18H,9,12,15-16,19H2,(H,31,33)
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 0.270n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315975
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES Cc1csc(n1)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C29H28N4O4S2/c1-21-20-38-29(31-21)39(35,36)32-28(34)12-11-25-10-8-23(19-33-15-4-14-30-33)18-27(25)37-16-13-22-7-9-24-5-2-3-6-26(24)17-22/h2-10,14-15,17-18,20H,11-13,16,19H2,1H3,(H,32,34)
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 0.350n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315976
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES Cc1ccc(cc1Cl)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C32H30ClN3O4S/c1-23-7-13-29(21-30(23)33)41(38,39)35-32(37)14-12-27-11-9-25(22-36-17-4-16-34-36)20-31(27)40-18-15-24-8-10-26-5-2-3-6-28(26)19-24/h2-11,13,16-17,19-21H,12,14-15,18,22H2,1H3,(H,35,37)
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 0.430n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315977
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES Clc1ccc(cc1Cl)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C31H27Cl2N3O4S/c32-28-12-11-27(20-29(28)33)41(38,39)35-31(37)13-10-25-9-7-23(21-36-16-3-15-34-36)19-30(25)40-17-14-22-6-8-24-4-1-2-5-26(24)18-22/h1-9,11-12,15-16,18-20H,10,13-14,17,21H2,(H,35,37)
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 0.450n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315969
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C31H29N3O4S/c35-31(33-39(36,37)29-9-2-1-3-10-29)16-15-27-14-12-25(23-34-19-6-18-32-34)22-30(27)38-20-17-24-11-13-26-7-4-5-8-28(26)21-24/h1-14,18-19,21-22H,15-17,20,23H2,(H,33,35)
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 0.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315966
PNG
(3-(4-((3-cyanophenoxy)methyl)-2-(2-(naphthalen-2-y...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccc(c2)C#N)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C35H28F2N2O5S/c36-32-14-13-31(21-33(32)37)45(41,42)39-35(40)15-12-28-11-9-26(23-44-30-7-3-4-25(19-30)22-38)20-34(28)43-17-16-24-8-10-27-5-1-2-6-29(27)18-24/h1-11,13-14,18-21H,12,15-17,23H2,(H,39,40)
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 0.510n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315983
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(3-morpholinophen...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1cccc(c1)N1CCOCC1
Show InChI InChI=1S/C31H32F2N4O5S/c32-28-9-8-27(21-29(28)33)43(39,40)35-31(38)10-7-25-6-5-24(22-37-13-2-12-34-37)20-30(25)42-16-11-23-3-1-4-26(19-23)36-14-17-41-18-15-36/h1-6,8-9,12-13,19-21H,7,10-11,14-18,22H2,(H,35,38)
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 0.540n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315974
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES Cc1ccc(o1)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C30H29N3O5S/c1-22-7-14-30(38-22)39(35,36)32-29(34)13-12-26-11-9-24(21-33-17-4-16-31-33)20-28(26)37-18-15-23-8-10-25-5-2-3-6-27(25)19-23/h2-11,14,16-17,19-20H,12-13,15,18,21H2,1H3,(H,32,34)
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 0.580n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315973
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1cccnc1
Show InChI InChI=1S/C30H28N4O4S/c35-30(33-39(36,37)28-7-3-15-31-21-28)13-12-26-11-9-24(22-34-17-4-16-32-34)20-29(26)38-18-14-23-8-10-25-5-1-2-6-27(25)19-23/h1-11,15-17,19-21H,12-14,18,22H2,(H,33,35)
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 1n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315965
PNG
(CHEMBL1092097 | N-(3,4-difluorophenylsulfonyl)-3-(...)
Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(CN2CCOCC2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C32H32F2N2O5S/c33-29-11-10-28(21-30(29)34)42(38,39)35-32(37)12-9-26-8-6-24(22-36-14-17-40-18-15-36)20-31(26)41-16-13-23-5-7-25-3-1-2-4-27(25)19-23/h1-8,10-11,19-21H,9,12-18,22H2,(H,35,37)
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 1.20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315972
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccccn1
Show InChI InChI=1S/C30H28N4O4S/c35-29(33-39(36,37)30-8-3-4-16-31-30)14-13-26-12-10-24(22-34-18-5-17-32-34)21-28(26)38-19-15-23-9-11-25-6-1-2-7-27(25)20-23/h1-12,16-18,20-21H,13-15,19,22H2,(H,33,35)
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 1.60n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152513
PNG
(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO4/c1-18-16-23-21(17-25(28)29)8-5-9-24(23)27(18)26(30)20-10-12-22(13-11-20)31-15-14-19-6-3-2-4-7-19/h2-13,16H,14-15,17H2,1H3,(H,28,29)
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 1.80n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50152515
PNG
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12
Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1
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 3.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50152512
PNG
(CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...)
Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2cc(F)ccc12
Show InChI InChI=1S/C28H25FN2O5/c1-17-12-23-19(13-27(32)33)4-3-5-24(23)31(17)28(34)18-6-9-21(10-7-18)35-16-22-15-30(2)25-11-8-20(29)14-26(25)36-22/h3-12,14,22H,13,15-16H2,1-2H3,(H,32,33)/t22-/m0/s1
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 5.30n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315964
PNG
(CHEMBL1090938 | N-(3,4-difluorophenylsulfonyl)-3-(...)
Show SMILES CN(C)Cc1ccc(CCC(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c(OCCc2ccc3ccccc3c2)c1
Show InChI InChI=1S/C30H30F2N2O4S/c1-34(2)20-22-8-10-24(11-14-30(35)33-39(36,37)26-12-13-27(31)28(32)19-26)29(18-22)38-16-15-21-7-9-23-5-3-4-6-25(23)17-21/h3-10,12-13,17-19H,11,14-16,20H2,1-2H3,(H,33,35)
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 8.20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152516
PNG
(CHEMBL184684 | {1-[4-(Benzo[1,3]dioxol-2-ylmethoxy...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2Oc3ccccc3O2)cc1
Show InChI InChI=1S/C26H21NO6/c1-16-13-20-18(14-24(28)29)5-4-6-21(20)27(16)26(30)17-9-11-19(12-10-17)31-15-25-32-22-7-2-3-8-23(22)33-25/h2-13,25H,14-15H2,1H3,(H,28,29)
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 9.40n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50152508
PNG
(CHEMBL364593 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc3O2)cc1
Show InChI InChI=1S/C27H23NO6/c1-17-13-22-19(14-26(29)30)5-4-6-23(22)28(17)27(31)18-9-11-20(12-10-18)32-15-21-16-33-24-7-2-3-8-25(24)34-21/h2-13,21H,14-16H2,1H3,(H,29,30)/t21-/m1/s1
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 10n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152508
PNG
(CHEMBL364593 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc3O2)cc1
Show InChI InChI=1S/C27H23NO6/c1-17-13-22-19(14-26(29)30)5-4-6-23(22)28(17)27(31)18-9-11-20(12-10-18)32-15-21-16-33-24-7-2-3-8-25(24)34-21/h2-13,21H,14-16H2,1H3,(H,29,30)/t21-/m1/s1
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 10n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152515
PNG
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12
Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1
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 10n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152506
PNG
(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
Show InChI InChI=1S/C26H23NO5/c1-18-16-23-20(17-25(28)29)6-5-9-24(23)27(18)26(30)19-10-12-22(13-11-19)32-15-14-31-21-7-3-2-4-8-21/h2-13,16H,14-15,17H2,1H3,(H,28,29)
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 10n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152507
PNG
(CHEMBL182555 | [1-(4-Butoxy-benzoyl)-2-methyl-1H-i...)
Show SMILES CCCCOc1ccc(cc1)C(=O)n1c(C)cc2c(CC(O)=O)cccc12
Show InChI InChI=1S/C22H23NO4/c1-3-4-12-27-18-10-8-16(9-11-18)22(26)23-15(2)13-19-17(14-21(24)25)6-5-7-20(19)23/h5-11,13H,3-4,12,14H2,1-2H3,(H,24,25)
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 10n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35855
PNG
(acrylic acid derivative, 4)
Show SMILES OC(=O)\C=C\c1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C25H22N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-11,13-14,16-17H,12,15,18H2,(H,28,29)/b11-10+
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 12n/an/an/a 73n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35861
PNG
(phenylpropanoic acid analogue, 5)
Show SMILES OC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C25H24N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-9,13-14,16-17H,10-12,15,18H2,(H,28,29)
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 12n/an/an/a 22n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315970
PNG
(CHEMBL1092267 | N-(4-((1H-pyrazol-1-yl)methyl)-2-(...)
Show SMILES O=C(NCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C30H28N4O4S/c35-30(33-39(36,37)28-9-2-1-3-10-28)31-21-27-14-12-24(22-34-17-6-16-32-34)20-29(27)38-18-15-23-11-13-25-7-4-5-8-26(25)19-23/h1-14,16-17,19-20H,15,18,21-22H2,(H2,31,33,35)
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 15n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35854
PNG
(acrylic acid derivative, 12)
Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C25H22N2O3/c28-25(29)10-9-22-8-6-20(17-27-13-12-26-18-27)16-24(22)30-14-11-19-5-7-21-3-1-2-4-23(21)15-19/h1-10,12-13,15-16,18H,11,14,17H2,(H,28,29)/b10-9+
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 16n/an/an/a 50n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50152509
PNG
(CHEMBL363984 | {1-[4-(2,3-Dihydro-benzofuran-2-ylm...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2Cc3ccccc3O2)cc1
Show InChI InChI=1S/C27H23NO5/c1-17-13-23-19(15-26(29)30)6-4-7-24(23)28(17)27(31)18-9-11-21(12-10-18)32-16-22-14-20-5-2-3-8-25(20)33-22/h2-13,22H,14-16H2,1H3,(H,29,30)
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 20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152509
PNG
(CHEMBL363984 | {1-[4-(2,3-Dihydro-benzofuran-2-ylm...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2Cc3ccccc3O2)cc1
Show InChI InChI=1S/C27H23NO5/c1-17-13-23-19(15-26(29)30)6-4-7-24(23)28(17)27(31)18-9-11-21(12-10-18)32-16-22-14-20-5-2-3-8-25(20)33-22/h2-13,22H,14-16H2,1H3,(H,29,30)
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 20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35861
PNG
(phenylpropanoic acid analogue, 5)
Show SMILES OC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C25H24N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-9,13-14,16-17H,10-12,15,18H2,(H,28,29)
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 21n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM50315968
PNG
(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)
Show SMILES CS(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C26H27N3O4S/c1-34(31,32)28-26(30)12-11-23-10-8-21(19-29-15-4-14-27-29)18-25(23)33-16-13-20-7-9-22-5-2-3-6-24(22)17-20/h2-10,14-15,17-18H,11-13,16,19H2,1H3,(H,28,30)
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 22n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter

Bioorg Med Chem Lett 20: 2639-43 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.034
BindingDB Entry DOI: 10.7270/Q23B6099
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50152516
PNG
(CHEMBL184684 | {1-[4-(Benzo[1,3]dioxol-2-ylmethoxy...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2Oc3ccccc3O2)cc1
Show InChI InChI=1S/C26H21NO6/c1-16-13-20-18(14-24(28)29)5-4-6-21(20)27(16)26(30)17-9-11-19(12-10-17)31-15-25-32-22-7-2-3-8-23(22)33-25/h2-13,25H,14-15H2,1H3,(H,28,29)
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 30n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35864
PNG
(phenylbutanoic acid analogue, 20)
Show SMILES OC(=O)CCCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C26H26N2O3/c29-26(30)8-3-7-23-12-10-21(19-28-15-4-14-27-28)18-25(23)31-16-13-20-9-11-22-5-1-2-6-24(22)17-20/h1-2,4-6,9-12,14-15,17-18H,3,7-8,13,16,19H2,(H,29,30)
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 39n/an/an/a 460n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35853
PNG
(acrylic acid derivative, 11)
Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCc1cc2ccccc2o1
Show InChI InChI=1S/C23H20N2O4/c26-23(27)8-7-18-6-5-17(15-25-11-10-24-16-25)13-22(18)28-12-9-20-14-19-3-1-2-4-21(19)29-20/h1-8,10-11,13-14,16H,9,12,15H2,(H,26,27)/b8-7+
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 44n/an/an/a 330n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50152514
PNG
(CHEMBL365829 | {1-[4-(Chroman-2-ylmethoxy)-benzoyl...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2CCc3ccccc3O2)cc1
Show InChI InChI=1S/C28H25NO5/c1-18-15-24-21(16-27(30)31)6-4-7-25(24)29(18)28(32)20-10-12-22(13-11-20)33-17-23-14-9-19-5-2-3-8-26(19)34-23/h2-8,10-13,15,23H,9,14,16-17H2,1H3,(H,30,31)
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 50n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152511
PNG
(CHEMBL365243 | [1-(4-Benzyloxy-benzoyl)-2-methyl-1...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C25H21NO4/c1-17-14-22-20(15-24(27)28)8-5-9-23(22)26(17)25(29)19-10-12-21(13-11-19)30-16-18-6-3-2-4-7-18/h2-14H,15-16H2,1H3,(H,27,28)
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 60n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Mus musculus (Mouse))		BDBM50152508
PNG
(CHEMBL364593 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc3O2)cc1
Show InChI InChI=1S/C27H23NO6/c1-17-13-22-19(14-26(29)30)5-4-6-23(22)28(17)27(31)18-9-11-20(12-10-18)32-15-21-16-33-24-7-2-3-8-25(24)34-21/h2-13,21H,14-16H2,1H3,(H,29,30)/t21-/m1/s1
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 60n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152514
PNG
(CHEMBL365829 | {1-[4-(Chroman-2-ylmethoxy)-benzoyl...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2CCc3ccccc3O2)cc1
Show InChI InChI=1S/C28H25NO5/c1-18-15-24-21(16-27(30)31)6-4-7-25(24)29(18)28(32)20-10-12-22(13-11-20)33-17-23-14-9-19-5-2-3-8-26(19)34-23/h2-8,10-13,15,23H,9,14,16-17H2,1H3,(H,30,31)
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 60n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35846
PNG
(acrylic acid derivative, 3)
Show SMILES Cc1c(C)c2OC(C)(CCOc3cc(Cn4ccnc4)ccc3\C=C\C(O)=O)CCc2c(C)c1O
Show InChI InChI=1S/C28H32N2O5/c1-18-19(2)27-23(20(3)26(18)33)9-10-28(4,35-27)11-14-34-24-15-21(16-30-13-12-29-17-30)5-6-22(24)7-8-25(31)32/h5-8,12-13,15,17,33H,9-11,14,16H2,1-4H3,(H,31,32)/b8-7+
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 63n/an/an/a 600n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Mus musculus (Mouse))		BDBM50152514
PNG
(CHEMBL365829 | {1-[4-(Chroman-2-ylmethoxy)-benzoyl...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2CCc3ccccc3O2)cc1
Show InChI InChI=1S/C28H25NO5/c1-18-15-24-21(16-27(30)31)6-4-7-25(24)29(18)28(32)20-10-12-22(13-11-20)33-17-23-14-9-19-5-2-3-8-26(19)34-23/h2-8,10-13,15,23H,9,14,16-17H2,1H3,(H,30,31)
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 90n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35862
PNG
(phenylpropynoic acid analogue, 18)
Show SMILES OC(=O)C#Cc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C25H20N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-9,13-14,16-17H,12,15,18H2,(H,28,29)
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 99n/an/an/a 1.20E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Mus musculus (Mouse))		BDBM50152515
PNG
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12
Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1
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 100n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))		BDBM35856
PNG
(acrylic acid derivative, 13)
Show SMILES OC(=O)\C=C\c1ccc(CN2CCCC2=O)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C26H25NO4/c28-25-6-3-14-27(25)18-20-8-10-22(11-12-26(29)30)24(17-20)31-15-13-19-7-9-21-4-1-2-5-23(21)16-19/h1-2,4-5,7-12,16-17H,3,6,13-15,18H2,(H,29,30)/b12-11+
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 110n/an/an/a 580n/an/an/an/a



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...

Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Mus musculus)		BDBM50152518
PNG
(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OC[C@H]2COc3ccccc3O2)cc1
Show InChI InChI=1S/C27H23NO6/c1-17-13-22-19(14-26(29)30)5-4-6-23(22)28(17)27(31)18-9-11-20(12-10-18)32-15-21-16-33-24-7-2-3-8-25(24)34-21/h2-13,21H,14-16H2,1H3,(H,29,30)/t21-/m0/s1
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 120n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50152518
PNG
(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Show SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OC[C@H]2COc3ccccc3O2)cc1
Show InChI InChI=1S/C27H23NO6/c1-17-13-22-19(14-26(29)30)5-4-6-23(22)28(17)27(31)18-9-11-20(12-10-18)32-15-21-16-33-24-7-2-3-8-25(24)34-21/h2-13,21H,14-16H2,1H3,(H,29,30)/t21-/m0/s1
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 130n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor

Bioorg Med Chem Lett 14: 4891-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.039
BindingDB Entry DOI: 10.7270/Q2BK1BTV
More data for this
Ligand-Target Pair
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