BDBM50152513 CHEMBL361457::[2-Methyl-1-(4-phenethyloxy-benzoyl)-1H-indol-4-yl]-acetic acid
SMILES: Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCc2ccccc2)cc1
InChI Key: InChIKey=JLYOJYCKWIZTAQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid DP receptor (Mus musculus) | BDBM50152513 (CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50152513 (CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50152513 (CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50152513 (CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50152513 (CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid DP receptor (Mus musculus) | BDBM50152513 (CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece... | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair |