| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
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| Ligand | BDBM50152513 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303670 (CHEMBL830431) |
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| Ki | 1900±n/a nM |
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| Citation |  Torisu, K; Kobayashi, K; Iwahashi, M; Nakai, Y; Onoda, T; Nagase, T; Sugimoto, I; Okada, Y; Matsumoto, R; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett14:4891-5 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP4 subtype |
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| Name: | Prostaglandin E2 receptor EP4 subtype |
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| Synonyms: | PE2R4_MOUSE | PGE receptor, EP4 subtype | Prostanoid EP4 receptor | Ptger4 | Ptgerep4 |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 56175.66 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 513 |
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| Sequence: | MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGN
LVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYS
TFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPN
MGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHR
QFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVI
LLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILL
RKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTS
QTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVD
EVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
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| BDBM50152513 |
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| n/a |
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| Name | BDBM50152513 |
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| Synonyms: | CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl)-1H-indol-4-yl]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C26H23NO4 |
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| Mol. Mass. | 413.4651 |
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| SMILES | Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCc2ccccc2)cc1 |
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| Structure | 
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