Reaction Details | |||
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Target | Melanocortin receptor 4 | ||
Ligand | BDBM50152796 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_303254 (CHEMBL826380) | ||
Ki | 25±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Melanocortin receptor 4 | |||
Name: | Melanocortin receptor 4 | ||
Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) | ||
Type: | Enzyme | ||
Mol. Mass.: | 36949.50 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P32245 | ||
Residue: | 332 | ||
Sequence: |
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BDBM50152796 | |||
n/a | |||
Name | BDBM50152796 | ||
Synonyms: | 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-2-(4-{2-[1-(4-amino-cyclohexylamino)-ethyl]-phenyl}-piperazin-1-yl)-1-(4-chloro-benzyl)-2-oxo-ethyl]-amide | CHEMBL366321 | ||
Type | Small organic molecule | ||
Emp. Form. | C37H47ClN6O2 | ||
Mol. Mass. | 643.261 | ||
SMILES | CC(NC1CCC(N)CC1)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 |wU:24.36,36.39,(-2.68,1.48,;-4,2.25,;-4,3.77,;-5.35,4.52,;-5.37,6.09,;-6.7,6.83,;-8.04,6.07,;-9.36,6.81,;-8.02,4.52,;-6.67,3.75,;-5.33,1.48,;-6.67,2.24,;-8.02,1.48,;-8.02,-.05,;-6.67,-.81,;-5.33,-.05,;-4,-.81,;-4,-2.34,;-2.66,-3.09,;-1.31,-2.34,;-1.31,-.81,;-2.66,-.05,;.01,-3.09,;.01,-4.62,;1.37,-2.35,;1.37,-.81,;2.12,.5,;1.33,1.8,;2.1,3.12,;3.65,3.15,;4.39,4.48,;4.45,1.83,;3.67,.51,;2.7,-3.12,;4.04,-2.35,;4.04,-.84,;5.39,-3.12,;6.71,-2.37,;8.06,-3.14,;9.38,-2.37,;10.72,-3.14,;10.72,-4.67,;9.38,-5.43,;8.06,-4.66,;6.71,-5.41,;5.38,-4.65,)| | ||
Structure | ![]() |