| Reaction Details |
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 | Report a problem with these data |
| Target | Cytoplasmic protein NCK1 |
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| Ligand | BDBM14322 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304472 (CHEMBL832688) |
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| EC50 | 150000±n/a nM |
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| Citation |  Inglis, SR; Stojkoski, C; Branson, KM; Cawthray, JF; Fritz, D; Wiadrowski, E; Pyke, SM; Booker, GW Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem47:5405-17 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytoplasmic protein NCK1 |
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| Name: | Cytoplasmic protein NCK1 |
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| Synonyms: | NCK | NCK1 | NCK1_HUMAN | Nck adaptor protein 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42863.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_304472 |
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| Residue: | 377 |
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| Sequence: | MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKN
SARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAE
REDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLA
AVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVG
LVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERG
HEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAP
IFTSEQGEKLYLVKHLS
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| BDBM14322 |
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| n/a |
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| Name | BDBM14322 |
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| Synonyms: | 2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL61236 | Fragment 19 | Quinolin-2-amine | fragment 2 (J. med. chem.,50,1116) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8N2 |
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| Mol. Mass. | 144.1732 |
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| SMILES | Nc1ccc2ccccc2n1 |
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| Structure | 
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