| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase |
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| Ligand | BDBM50154586 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302256 (CHEMBL829490) |
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| Kd | 22000±n/a nM |
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| Citation |  Inglis, SR; Stojkoski, C; Branson, KM; Cawthray, JF; Fritz, D; Wiadrowski, E; Pyke, SM; Booker, GW Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem47:5405-17 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase |
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| Name: | Tyrosine-protein kinase |
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| Synonyms: | Q8CFK4_MOUSE | Tec | Tyrosine-protein kinase TEC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 71010.89 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_304473 |
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| Residue: | 608 |
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| Sequence: | MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLSYYEGRAEKKYRKGVIDISKIK
CVEIVKNDDGVIPCQNKFPFQVVHDANTLYIFAPSPQSRDRWVKKLKEEIKNNNNIMIKY
HPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKKRRPPPPIPPEEENTE
EIVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGWYCRNTNRSKAEQLLRT
EDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSI
PEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGV
VRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTE
FMERGCLLNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVV
KVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGR
MPFEKNTNYEVVTMVTRGHRLHRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELV
ECEETFGR
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| BDBM50154586 |
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| n/a |
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| Name | BDBM50154586 |
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| Synonyms: | 6-(5,5-Dimethyl-[1,3]dioxan-2-yl)-quinolin-2-ylamine | CHEMBL185932 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N2O2 |
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| Mol. Mass. | 258.3156 |
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| SMILES | CC1(C)COC(OC1)c1ccc2nc(N)ccc2c1 |
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| Structure | 
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