| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase haspin |
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| Ligand | BDBM50587766 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2185218 (CHEMBL5097300) |
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| Kd | 0.019±n/a nM |
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| Citation |  Lee, S; Kim, J; Jo, J; Chang, JW; Sim, J; Yun, H Recent advances in development of hetero-bivalent kinase inhibitors. Eur J Med Chem216:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase haspin |
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| Name: | Serine/threonine-protein kinase haspin |
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| Synonyms: | GSG2 | Germ cell-specific gene 2 protein | H-haspin | HASPIN | HASP_HUMAN | Haploid germ cell-specific nuclear protein kinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88531.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1510616 |
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| Residue: | 798 |
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| Sequence: | MAASLPGPGSRLFRTYGAADGRRQRRPGREAAQWFPPQDRRRFFNSSGSSDASIGDPSQS
DDPDDPDDPDFPGSPVRRRRRRPGGRVPKDRPSLTVTPKRWKLRARPSLTVTPRRLGLRA
RPPQKCSTPCGPLRLPPFPSRDSGRLSPDLSVCGQPRDGDELGISASLFSSLASPCPGSP
TPRDSVISIGTSACLVAASAVPSGLHLPEVSLDRASLPCSQEEATGGAKDTRMVHQTRAS
LRSVLFGLMNSGTPEDSEFRADGKNMRESCCKRKLVVGNGPEGPGLSSTGKRRATGQDSC
QERGLQEAVRREHQEASVPKGRIVPRGIDRLERTRSSRKSKHQEATETSLLHSHRFKKGQ
KLGKDSFPTQDLTPLQNVCFWTKTRASFSFHKKKIVTDVSEVCSIYTTATSLSGSLLSEC
SNRPVMNRTSGAPSSWHSSSMYLLSPLNTLSISNKKASDAEKVYGECSQKGPVPFSHCLP
TEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISK
ELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLF
IVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKT
SLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFD
IYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRT
MLNFSSATDLLCQHSLFK
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| BDBM50587766 |
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| n/a |
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| Name | BDBM50587766 |
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| Synonyms: | CHEMBL5199572 |
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| Type | Small organic molecule |
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| Emp. Form. | C60H100IN23O19 |
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| Mol. Mass. | 1574.4832 |
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| SMILES | C[C@H](O)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCNC(=O)C[C@@H](NC(=O)CCCCCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(I)c2c(N)ncnc12)C(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)N[C@H](CCCCN)C(N)=O |r| |
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| Structure | 
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