| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50590648 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2197386 (CHEMBL5109902) |
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| Ki | 2.2±n/a nM |
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| Citation |  Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors. J Med Chem65:10755-10808 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50590648 |
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| n/a |
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| Name | BDBM50590648 |
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| Synonyms: | CHEMBL5202019 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H71FN10O5Si |
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| Mol. Mass. | 926.2385 |
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| SMILES | [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-n2cc(-[#6]-[#8]-[#6]-[#6](-[#6]-[#8]-c3ccc(cc3)[Si;v4]([18F])(C([#6])([#6])[#6])C([#6])([#6])[#6])-[#8]-[#6]-c3cn(-[#6]-[#6]-[#7]-4-[#6]-[#6]-[#7](-[#6]-[#6]-4)-c4ccccc4-[#8]-[#6])nn3)nn2)-[#6]-[#6]-1 |
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| Structure | 
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